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Molfinity

ND-011992 - CAS 2446880-46-0

ND-011992 - CAS 2446880-46-0

SKU:MF-0119732-01

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  • Bioactivity

    ND-011992 is a reversible and selective quinazoline inhibitor targeting quinone reductases and quinol oxidases.ND-011992 inhibits E. coli BL21*Δcyo respiratory complex I. ND-011992 inhibits bo3 oxidase, bd-I oxidases and bd-II oxidases, ND-011992 inhibits E. coli BL21*Δcyo respiratory complex I, bo3 oxidase, bd-I oxidases, and bd-II oxidases with IC50s of 0.12, 2.47, 0.63, and 1.3 μM, respectively.ND-011992 can be used in the study of tuberculosis.

  • Target

    Mitochondrial Metabolism, Antibacterial

  • Related Pathways

    Microbiology/Virology, Metabolism

  • CAS Number

    2446834

  • Purity

    0.9999

  • Molecular Formula

    C21H14F3N3O

  • Molecular Weight

    381.35

  • SMILES

    N(C=1C2=C(N=CN1)C=CC=C2)C3=CC=C(OC4=CC=C(C(F)(F)F)C=C4)C=C3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound