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Molfinity

NDI-034858 - CAS 2272904-53-5

NDI-034858 - CAS 2272904-53-5

MF-0096503-01

$280.78 USD
$280.78 USD
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Product Details

  • Bioactivity

    NDI-034858 (TAK-279) is a tyrosine kinase 2 (TYK2) inhibitor (Kd<200 pM) that targets the JH2 structural domain of Tyk2 for the treatment of autoimmune diseases caused by aberrant expression of IL12 and IL23.

  • Target

    Tyrosine Kinases, JAK, IL Receptor

  • Related Pathways

    Immunology/Inflammation, Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, Angiogenesis, JAK/STAT signaling, Stem Cells

  • CAS Number

    2272846

  • Purity

    >99.99%

  • Molecular Formula

    C23H24N8O3

  • Molecular Weight

    460.49

  • SMILES

    CNc1cc(Nc2cccn(-c3ccccn3)c2=O)nc2c(cnn12)C(=O)N[C@@H]1CC[C@H]1OC

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound