Molfinity

NDI-091143 - CAS 2375840-87-0

SKU:MF-0016954-01

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Size 1 mg 5 mg 1 mL - 10 mM (in DMSO) 10 mg 25 mg 50 mg 100 mg

Product Details

Bioactivity
NDI-091143 is a potent, high-affinity human ATP-citrate lyase (ACLY) inhibitor with an IC50 of 2.1 nM (ADP-Glo assay), indirectly disrupting citrate binding via an unexpected mechanism of inhibition.
Target
ATP Citrate Lyase
Related Pathways
Metabolism
CAS Number
2375753
Purity
0.9861
Molecular Formula
C20H14ClF2NO5S
Molecular Weight
453.84
SMILES
COC(=O)c1cc(Cl)c(O)c(c1)S(=O)(=O)Nc1cc(c(F)cc1F)-c1ccccc1
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound