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NDT-19795 - CAS 2272917-12-9
NDT-19795 - CAS 2272917-12-9
SKU:MF-0121020-01
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Product Details
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Bioactivity
NDT-19795 is a potent NLRP3 inflammasome inhibitor with an IC 50 value of 66 nM using the PBMC method and 4.7 μM using the WB method. It is a carboxylic acid-active compound that can be derived from NT-0796 within cells, and is applicable for neurological disease research [1].
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Target
NOD-like Receptor (NLR)
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Related Pathways
Immunology/Inflammation
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CAS Number
2272917-12-9
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Molecular Formula
C20H21N3O4
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Molecular Weight
367.4
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SMILES
N(C(O[C@H](CC=1N=CC=CN1)C(O)=O)=O)C2=C3C(=CC4=C2CCC4)CCC3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound