1 1

Molfinity

Nec-3a - CAS 1504558-72-8

Nec-3a - CAS 1504558-72-8

MF-0146762-01

$1,383.80 USD
$1,383.80 USD
Sale Sold out
Taxes included.
Size
View full details

Product Details

  • Bioactivity

    Nec-3a, an analogue of Necrostatin-3, acts as a RIP1 inhibitor with an inhibition concentration (IC50) of 0.44 μM. This compound successfully impedes the autophosphorylation activity within the RIP1 kinase domain.

  • Target

    Others, RIP kinase

  • Related Pathways

    Apoptosis, Others, NF-κB

  • CAS Number

    1504478

  • Molecular Formula

    C21H18F4N2O4

  • Molecular Weight

    438.37

  • SMILES

    C(CO)(=O)N1[C@@H]([C@]2(C(=N1)C=3C(CC2)=CC=C(OC)C3)[H])C4=CC(F)=C(OC(F)(F)F)C=C4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound