Necrocide 1 - CAS 1247028-61-0

Necrocide 1 is a potent inducer of cancer cell necrosis that is not inhibited by caspase blockers, anti-apoptotic BCL2 overexpression, or TNFα neutralization at nanomolar concentrations, and acts through the mitochondrial regulatory pathway.

TRP/TRPV Channel, ROS, PERK, Others, Necroptosis

Immunology/Inflammation, Membrane transporter/Ion channel, Others, Apoptosis

1246967

C23H27NO3

365.47

O=C1[C@](C=2C(N1)=C(C)C(OC)=CC2)(C3=CC=C(O)C=C3)C4CCCCCC4

-20°C

Ice Packs

Small Compound