Necrostatin-34 - CAS 375835-43-1

Necrostatin-34 (2-{[3-cyano-4- (4-methylphenyl) -6-oxo-1,4) is a RIPK1 kinase inhibitor, stabilizing RIPK1 kinase in an inactive conformation by occupying a distinct binding pocket in the kinase domain.

RIP kinase

Apoptosis, NF-κB

375835-43-1

0.988

C18H16N4O2S2

384.48

Cc1ccc(cc1)C1CC(=O)NC(SCC(=O)Nc2nccs2)=C1C#N

-20°C

Ice Packs

Small Compound