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Molfinity

Necrostatin-5 - CAS 337349-54-9

Necrostatin-5 - CAS 337349-54-9

MF-0109968-01

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Product Details

  • Bioactivity

    Necrostatin-5 (Nec-5) is a selective RIP1 kinase inhibitor and cell necrosis inhibitor that prevents the death of Fadd-deficient Jurkat cells treated with TNF-α, with an EC50 of 240 nM.

  • Target

    Necroptosis, RIP kinase

  • Related Pathways

    Apoptosis, NF-κB

  • CAS Number

    337286

  • Purity

    0.994

  • Molecular Formula

    C19H17N3O2S2

  • Molecular Weight

    383.49

  • SMILES

    O=C1C=2C3=C(SC2N=C(SCC#N)N1C4=CC=C(OC)C=C4)CCCC3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound