Necrosulfonamide - CAS 1360614-48-7

Necrosulfonamide ((E) -Necrosulfonamide) is a necroptosis inhibitor that targets MLKL and is selective. Necrosulfonamide prevents the MLKL-RIP1-RIP3 necrosomal complex from interacting with its downstream effectors.

PI4K, PI3K, MLK

PI3K/Akt/mTOR signaling, MAPK

1360559

0.9949

C18H15N5O6S2

461.47

COc1nccnc1NS(=O)(=O)c1ccc(NC(=O)\C=C\c2ccc(s2)[N+]([O-])=O)cc1

-20°C

Ice Packs

Small Compound