Nedaplatin - CAS 95734-82-0

Nedaplatin (NSC-375101D) is a derivative of cisplatin and DNA damage agent for tumor colony forming units (IC50: 94 μM) . Containing a novel ring structure in which glycolate is bound to the platinum by a bidentate ligand, nedaplatin forms reactive platinum complexes that bind to nucleophilic groups in DNA, resulting in intrastrand and interstrand DNA cross-links, apoptosis and cell death.

DNA/RNA Synthesis

Cell Cycle/Checkpoint, DNA Damage/DNA Repair

95652

>99.99%

C2H8N2O3Pt

303.17

N.N.[Pt++].[O-]CC([O-])=O

-20°C

Ice Packs

Small Compound