NEK7-IN-1 - CAS 2738569-12-3

NEK7-IN-1 (Compound I-15) is an inhibitor of NIMA-related kinase 7 (NEK7) with an IC50 of less than 100 nM. It also effectively inhibits the release of IL-1β, exhibiting an IC50 of less than 50 nM.

MAPK, Others

Others, MAPK

2738554

C30H34F4N8O2

614.64

O=C(NC1=CC=C(C(=C1)C(F)(F)F)CN2CCN(C)CC2)NC=3C=CC(=CC3F)C4=CN(C=5N=CN=C(N)C45)CC(O)(C)C

-20°C

Ice Packs

Small Compound