Neochamaejasmine A - CAS 90411-13-5

Neochamaejasmin A can inhibit cellular (3) H-thymidine incorporation (IC 50 12.5 microg/mL) and subsequent proliferation of human prostate cancer LNCaP cells, it blocks cell cycle progression at the G1 phase by activating the p21 protein and ultimately promoting the Fas-caspase 8-caspase 3 apoptotic machinery.

Apoptosis, Caspase

Apoptosis, Proteases/Proteasome

90393

C30H22O10

542.49

O=C1[C@]([C@H](OC=2C1=C(O)C=C(O)C2)C3=CC=C(O)C=C3)([C@]4([C@H](OC=5C(C4=O)=C(O)C=C(O)C5)C6=CC=C(O)C=C6)[H])[H]

-20°C

Ice Packs

Natural Product