Nepaprazole sodium - CAS 157564-11-9

Nepaprazole Na is the salt form of Nepaprazole Free Base, also known as TY-11345, is a proton pump inhibitor potentially for treatment of gastric ulcer. TY-11345 potently inhibited H+/K (+) -ATPase activity in isolated rabbit gastric mucosal microsomes; and the inhibitory effect was enhanced under weak acid conditions, the IC50 (concentrations that inhibit the enzyme activity by 50%) being 5.8 microM and 9.9 microM at pH 6.0 and pH 7.4, respectively. TY-11345 should be useful for the clinical treatment of peptic ulcer diseases.

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Others

157544

C18H18N3NaO2S

363.41

[Na+].[H][C@]1(CCCCc2c(OC)ccnc12)S(=O)c1nc2ccccc2[n-]1

-20°C

Ice Packs

Small Compound