Skip to product information
1 of 1

Molfinity

Neriifolin - CAS 466-07-9

Neriifolin - CAS 466-07-9

SKU:MF-0024233

Regular price $145.25 USD
Regular price Sale price $145.25 USD
Sale Sold out
Taxes included.
Size
Quantity
View full details
  • Bioactivity

    Neriifolin (17β-Neriifolin), a cardiac glycoside extracted from the unripe fruit of Cerbera manghas, is a Na+K+-ATPase inhibitor with anticancer activity that inhibits cell proliferation by suppressing HOXA9-dependent gene expression and inducing apoptosis in the human acute myeloid cell line, THP-1. Neriifolin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells and can be used in prostate cancer research.

  • Target

    Apoptosis, ATPase, Autophagy, ATG

  • Related Pathways

    Autophagy, Membrane transporter/Ion channel, Apoptosis

  • CAS Number

    466-07-9

  • Molecular Formula

    C30H46O8

  • Molecular Weight

    534.68

  • SMILES

    O[C@@]12[C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@@H](O[C@H]5[C@@H](O)[C@H](OC)[C@@H](O)[C@H](C)O5)CC4)[H])(CC[C@]1(C)[C@H](CC2)C6=CC(=O)OC6)[H])[H]

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Natural Product