Neuraminidase-IN-18 - CAS 2935407-32-0

Neuraminidase-IN-18 (compound N5), a novel polyheterocyclic neuraminidase (NA) inhibitor, demonstrates significant inhibitory activity against H5N1 NA, with an IC 50 of 0.14 μM against the wild-type H5N1 NA and 0.27 μM against the H5N1-H274Y mutant NA. This compound effectively binds to NAs, inhibiting influenza virus replication at the cellular level [1].

Influenza Virus

Microbiology/Virology

2935407-32-0

C22H18FN3O3S

423.46

O(CC=1OC(SCC(NCC2=CC=C(F)C=C2)=O)=NN1)C3=CC4=C(C=C3)C=CC=C4

-20°C

Ice Packs

Small Compound