Neuropeptide AF (cattle) - CAS 99588-52-0

Neuropeptide AF (cattle), an amidated octadecapeptide and RFamide neuropeptide, serves as a ligand for Mas-related gene receptor A4 (MrgprA4) (Mas-related G-protein-coupled Receptor (MRGPR) ) with an EC50 of approximately 60 nM, and MrgprC11 with an EC50 of around 300 nM. It activates G protein-coupled receptors NPFF1 (Neuropeptide Y Receptor) with an EC50 ranging from ~25 to 325 nM, and NPFF2 with an EC50 of approximately 1 to 5 nM. Additionally, Neuropeptide AF (cattle) exhibits anti-opiate effects and modulates related pain [1] [2].

Neuropeptide Y Receptor, MRGPR

GPCR/G Protein, Neuroscience

99536

C89H130N24O24

1920.13

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-20°C

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