Nexinhib20 - CAS 331949-35-0

Nexinhib20 is an inhibitor of exosome synthesis and transport with anti-inflammatory activity, inhibits RAB27A and neutral sphingomyelinase 2 (nSMase2) nsMase2, inhibits IL-8-induced β (2) integrin-dependent adhesion of human neutrophils in the subfluidic phase, and inhibits neutrophil adhesion and β (2) integrin activation through antagonism of the rac-1-guanosine 5'-triphosphate interaction. beta (2) integrin activation.

ROS, Ras, Integrin, Reactive Oxygen Species

Cytoskeletal Signaling, NF-κB, Metabolism, MAPK, GPCR/G Protein, Immunology/Inflammation

331914

0.9989

C15H16N4O3

300.31

O=C(C(C)(C)C)C(N1N=CN=C1)=CC2=CC=CC([N+]([O-])=O)=C2

-20°C

Ice Packs

Small Compound