NF-1819 - CAS 1881244-28-5

NF-1819 is a potent and selective irreversible MGL (β-lactam-based monoacylglycerol lipase) inhibitor. NF-1819 alleviates symptoms in a MS model in vivo and exhibits analgesic effects in an acute inflammatory pain model in vivo. NF-1819 displays high membrane permeability and brain penetrant.

MAGL, Lipase

Metabolism

1881211

0.9955

C24H22FN5O4

463.46

[H][C@@]1(N(C2CCN(CC2)C(=O)n2cncn2)C(=O)[C@]1([H])c1ccc(F)cc1)c1ccc2OCOc2c1

-20°C

Ice Packs

Small Compound