NF-56-EJ40 hydrochloride - CAS 2728500-80-7

NF-56-EJ40 hydrochloride is a potent, high-affinity, and highly selective human SUCNR1 (GPR91) antagonist with an IC50 of 25 nM and a Ki of 33 nM, and shows almost no activity towards rat SUCNR1. NF-56-EJ40 hydrochloride has high affinity for humanized rat SUCNR1 with a Ki value of 17.4 nM.

Succinate Receptor 1 (SUCNR1)

GPCR/G Protein

2728413

0.9933

C27H31Cl2N3O3

516.46

O=C(CC1=C(NC(C2=CC=CC(C3=CC=C(CN4CCN(CC4)C)C=C3)=C2)=O)C=CC=C1)O.Cl.Cl

-20°C

Ice Packs

Small Compound