NF-κB-IN-5 - CAS 2425675-52-9

NF-κB-IN-5 (compound 4d) is an orally active NF-κB inhibitor that interacts directly with NF-κB, and exhibits antitumor activity against human cancer cell lines, with IC50 values of 5.35, 2.81, 2.83, 2.02, and 3.90 μM for HCT116, U87-MG, HepG2, BGC823, and PC9, respectively.

Others, Apoptosis, NF-κB

Others, NF-κB, Apoptosis

2425614

C23H27N3O4

409.48

C[C@]12[C@@]([C@@]3([C@](C(=C)C(=O)O3)(CC/C(/C=N/NC(NC4=CC=C(C)C=C4)=O)=C\CC1)[H])[H])(O2)[H]

-20°C

Ice Packs

Small Compound