β-NF-JQ1 - CAS 2380000-55-3

β-NF-JQ1 is a PROTAC that recruits aryl hydrocarbon receptor E3 (AhR E3) ligase to target proteins. Using β-NF as an AhR ligand, it targets bromodomain (BRD) -containing proteins and induces AhR and BRD protein interactions. β-NF-JQ1 exhibits potent anticancer activity associated with protein knockdown activity.

PROTACs, Epigenetic Reader Domain

PROTAC, Chromatin/Epigenetic

2379942

0.9945

C45H42ClN5O6S

816.36

CC=1C2=C(N3C([C@H](CC(NCCOCCOCCOCC4=CC=C(C=C4)C=5OC=6C(C(=O)C5)=C7C(=CC6)C=CC=C7)=O)N=C2C8=CC=C(Cl)C=C8)=NN=C3C)SC1C

-20°C

Ice Packs

PROTAC