NFATc1-IN-1 - CAS 1912422-56-0

NFATc1-IN-1 (also known as compound A04) is a highly effective inhibitor of osteoclast formation induced by RANKL, with an IC50 of 1.57 μM. It exerts its anti-osteoclastogenic effects by attenuating the RANKL-induced nuclear translocation of NFATc1. Due to its remarkable properties, NFATc1-IN-1 holds significant potential for advancing research related to osteoclastic diseases [1].

RANKL/RANK, Others

Others, NF-κB

1912366

0.9998

C13H8F2INO2

375.11

C(NC1=C(F)C=C(I)C=C1)(=O)C2=C(O)C=CC(F)=C2

-20°C

Ice Packs

Small Compound