NG-497 - CAS 2598242-66-9

NG-497 is a selective, small molecule inhibitor of human adipose triglyceride lipase (ATGL) that targets the enzymatically active patatin-like structural domain of human ATGL.NG-497 binds ATGL in a hydrophobic lumen adjacent to the active site.NG-497 abrogates lipolysis in human adipocytes in a dose-dependent and reversible manner.NG-497 has been shown to be useful in cancer research. can be used in cancer research.

Lipase

Metabolism

2598167

0.9957

C18H21NO4

315.36

C(OC(C)C)(=O)C1=NC(=CC(OC)=C1)C2=CC=C(OCC)C=C2

-20°C

Ice Packs

Small Compound