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Molfinity

NGB 2904 - CAS 189060-98-8

NGB 2904 - CAS 189060-98-8

SKU:MF-0018520-01

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  • Bioactivity

    NGB 2904 is a potent and selective antagonist of dopamine D3 receptor (Ki values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D3, D2, 5-HT2, α1, D4, D1 and D5 receptors respectively) . NGB2904 potently antagonizes mitogenesis stimulated by quinpirole (IC50 = 6.8 nM) .

  • Target

    Dopamine Receptor, 5-HT Receptor

  • Related Pathways

    Neuroscience, GPCR/G Protein

  • CAS Number

    188954

  • Purity

    0.9935

  • Molecular Formula

    C28H29Cl2N3O

  • Molecular Weight

    494.46

  • SMILES

    Clc1cccc(N2CCN(CCCCNC(=O)c3ccc-4c(Cc5ccccc-45)c3)CC2)c1Cl

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound