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Molfinity

NH-3 - CAS 447415-26-1

NH-3 - CAS 447415-26-1

MF-0019914-01

$250.95 USD
$250.95 USD
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Product Details

  • Bioactivity

    NH-3 is a potent orally active thyroid hormone receptor (THR) antagonist which exhibits reversible behavior, demonstrated by an IC 50 of 55 nM. Derived from the selective thyromi-metic GC-1, NH-3 effectively inhibits the binding of thyroid hormones to their respective receptors, resulting in hindered cofactor recruitment.

  • Target

    Thyroid hormone receptor (THR)

  • Related Pathways

    Endocrinology/Hormones

  • CAS Number

    447388

  • Purity

    0.994

  • Molecular Formula

    C28H27NO6

  • Molecular Weight

    473.52

  • SMILES

    CC(C)c1cc(Cc2c(C)cc(OCC(O)=O)cc2C)cc(C#Cc2ccc(cc2)[N+]([O-])=O)c1O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound