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NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT - CAS 2857037-69-3
NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT - CAS 2857037-69-3
SKU:MF-0154940-01
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Product Details
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Bioactivity
Compound I, NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT, is a topoisomerase I inhibitor with the capability for targeted delivery to cells via conjugated antibodies. It exhibits effective ADC activity both in vivo and in vitro [1].
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Target
ADC Cytotoxin, Topoisomerase
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Related Pathways
Antibody-drug Conjugate/ADC Related, DNA Damage/DNA Repair
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CAS Number
2856965
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Molecular Formula
C26H23N3O6
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Molecular Weight
473.48
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SMILES
CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cc5OCOc5cc4c(c3Cn1c2=O)C12CC(N)(C1)C2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound