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NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT - CAS 2857037-69-3

NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT - CAS 2857037-69-3

SKU:MF-0154940-01

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  • Bioactivity

    Compound I, NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT, is a topoisomerase I inhibitor with the capability for targeted delivery to cells via conjugated antibodies. It exhibits effective ADC activity both in vivo and in vitro [1].

  • Target

    ADC Cytotoxin, Topoisomerase

  • Related Pathways

    Antibody-drug Conjugate/ADC Related, DNA Damage/DNA Repair

  • CAS Number

    2856965

  • Molecular Formula

    C26H23N3O6

  • Molecular Weight

    473.48

  • SMILES

    CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cc5OCOc5cc4c(c3Cn1c2=O)C12CC(N)(C1)C2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound