NH2-c[X-R-L-S-X]-K-G-P- (D-1Nal) - CAS 2891469-80-8

Compound 39 (NH2-c[X-R-L-S-X]-K-G-P- (D-1Nal) ) is a potent agonist of the APJ receptor, possessing a K i value of 0.6 nM. It is capable of activating Gαi1, with an EC 50 of 0.8 nM, and of recruiting β-arrestin2, with an EC 50 of 31 nM. Furthermore, this compound demonstrates extended effects on cardiac function [1].

Apelin receptor, Others

Others, GPCR/G Protein

2891381

C49H73N13O11

1020.18

-20°C

Ice Packs

Small Compound