NH2-c[X-R-L-S-X]-K-G-P- (D-2Nal) - CAS 2891469-81-9

Compound 40, NH2-c[X-R-L-S-X]-K-G-P- (D-2Nal), a macrocyclic analogue of Ape13, acts as a potent APJ agonist with a Ki of 5.7 nM. It demonstrates favorable Gα12-biased signaling and possesses an enhanced in vivo half-life [1].

Apelin receptor, Others

GPCR/G Protein, Others

2891379

C49H73N13O11

1020.18

-20°C

Ice Packs

Small Compound