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NHE3-IN-3 - CAS 543734-50-5

NHE3-IN-3 - CAS 543734-50-5

MF-0036977-01

$1,383.80 USD
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Product Details

  • Bioactivity

    NHE3-IN-3 (Compound 1) is a potent inhibitor of isoform 3 of the Na+/H+ exchanger (NHE3), exhibiting pIC50 values of 6.2 and 6.6 against human and rat NHE3, respectively, and demonstrates exceptional oral bioavailability of 98% in Sprague–Dawley rats [1].

  • Target

    Others, Sodium Channel

  • Related Pathways

    Others, Membrane transporter/Ion channel

  • CAS Number

    543734-50-5

  • Molecular Formula

    C16H16Cl2N2O2S

  • Molecular Weight

    371.28

  • SMILES

    CN1CC(C=2C(C1)=C(Cl)C=C(Cl)C2)C3=CC(S(N)(=O)=O)=CC=C3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound