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Molfinity

NHWD-870 - CAS 2115742-03-3

NHWD-870 - CAS 2115742-03-3

SKU:MF-0141911-01

Regular price $1,480.33 USD
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  • Bioactivity

    NHWD-870 is an effective and selective inhibitor of BET family bromodomain only binding to BRD2, BRD3, BRD4 (IC50 = 2.7 nM), and BRDT. NHWD-870 exhibits potent anti-tumor efficacies and suppresses cancer cell-macrophage interaction through the increase of tumor apoptosis and inhibition of tumor proliferation.

  • Target

    Apoptosis, Epigenetic Reader Domain

  • Related Pathways

    Apoptosis, Chromatin/Epigenetic

  • CAS Number

    2115742-03-3

  • Molecular Formula

    C29H29N7O

  • Molecular Weight

    491.59

  • SMILES

    Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc3n(C)ncc3cc21

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound