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NHWD-870 - CAS 2115742-03-3
NHWD-870 - CAS 2115742-03-3
SKU:MF-0141911-01
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$1,480.33 USD
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$1,480.33 USD
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Product Details
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Bioactivity
NHWD-870 is an effective and selective inhibitor of BET family bromodomain only binding to BRD2, BRD3, BRD4 (IC50 = 2.7 nM), and BRDT. NHWD-870 exhibits potent anti-tumor efficacies and suppresses cancer cell-macrophage interaction through the increase of tumor apoptosis and inhibition of tumor proliferation.
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Target
Apoptosis, Epigenetic Reader Domain
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Related Pathways
Apoptosis, Chromatin/Epigenetic
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CAS Number
2115742-03-3
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Molecular Formula
C29H29N7O
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Molecular Weight
491.59
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SMILES
Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc3n(C)ncc3cc21
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound