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Molfinity

NI-42 - CAS 1884640-99-6

NI-42 - CAS 1884640-99-6

SKU:MF-0013892-01

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  • Bioactivity

    NI-42 is a structurally orthogonal chemical probe for the BRPFs and is biased. It effective inhibitor of the BRD of the BRPFs (IC50s of BRPF1/2/3=7.9/48/260 nM; Kds of BRPF1/2/3=40/210/940 nM) . It also has excellent selectivity over nonclass IV BRD proteins.

  • Target

    Epigenetic Reader Domain

  • Related Pathways

    Chromatin/Epigenetic

  • CAS Number

    1884535

  • Purity

    0.9918

  • Molecular Formula

    C18H15N3O3S

  • Molecular Weight

    353.39

  • SMILES

    Cc1cc2cc(NS(=O)(=O)c3ccc(cc3)C#N)ccc2n(C)c1=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound