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Molfinity

NICE-01 - CAS 2982819-94-1

NICE-01 - CAS 2982819-94-1

SKU:MF-0158964-01

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  • Bioactivity

    NICE-01 (AP1867-PEG2-JQ1; AP-PEG2-JQ1) is a bifunctional compound that facilitates the nuclear import of cytosolic cargoes by utilizing the nuclear-localized bromodomain-containing protein 4 (BRD4) as a carrier for co-import and subsequent nuclear entrapment [1].

  • Target

    Others, Epigenetic Reader Domain

  • Related Pathways

    Chromatin/Epigenetic, Others

  • CAS Number

    2982819-94-1

  • Molecular Formula

    C63H76ClN7O13S

  • Molecular Weight

    1206.84

  • SMILES

    CC=1C2=C(N3C([C@H](CC(NCCOCCOCCNC(COC4=CC([C@H](OC(=O)[C@H]5N(C([C@@H](CC)C6=CC(OC)=C(OC)C(OC)=C6)=O)CCCC5)CCC7=CC(OC)=C(OC)C=C7)=CC=C4)=O)=O)N=C2C8=CC=C(Cl)C=C8)=NN=C3C)SC1C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Peptide