Niclosamide sodium - CAS 40321-86-6

Niclosamide sodium (BAY2353), an orally active antihelminthic agent employed in parasitic infection research, serves as a potent STAT3 inhibitor, demonstrating an IC50 of 0.25 μM in HeLa cells. Additionally, this compound exhibits significant biological activities against cancer and effectively inhibits DNA replication in Vero E6 cells.

Antibiotic, Others, STAT, Parasite

Microbiology/Virology, JAK/STAT signaling, Others, Stem Cells

40229

C13H7Cl2N2NaO4

349.1

O=[N+]([O-])C1=CC(Cl)=C(NC(C2=C([O-])C=CC(Cl)=C2)=O)C=C1.[Na+]

-20°C

Ice Packs

Small Compound