Nictide - CAS 1159973-22-4

Nictide, a peptide substrate for LRRK2 (leucine-rich repeat protein kinase-2), undergoes phosphorylation by the activated form of LRRK2[G2019S], exhibiting a Km value of 10 μM.

LRRK2

Autophagy

1159973-22-4

C123H193N45O28

2750.13

C([C@H](NC([C@H](CC=1C=2C(NC1)=CC=CC2)NC(CNC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)CC(C)C)=O)=O)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=C(O)C=C3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CCC(N)=O)=O)CCCCN)=O)[C@@H](C)O)=O)CC(N)=O)=O)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)C)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CC(C)C)=O)[C@@H](C)O)=O)=O)CC4=CC=CC=C4)=O)CCCNC(=N)N)=O)C=5C=6C(NC5)=CC=CC6

-20°C

Ice Packs

Peptide