Nifedipine - CAS 21829-25-4

Nifedipine (Procardia) is a dihydropyridine calcium channel blocking agent. Nifedipine inhibits the transmembrane influx of extracellular calcium ions into myocardial and vascular smooth muscle cells, causing dilatation of the main coronary and systemic arteries and decreasing myocardial contractility. This agent also inhibits the drug efflux pump P-glycoprotein which is overexpressed in some multi-drug resistant tumors and may improve the efficacy of some antineoplastic agents.

Calcium Channel, CaMK, Potassium Channel, Autophagy

Autophagy, Membrane transporter/Ion channel, Metabolism, Neuroscience

21800

0.9949

C17H18N2O6

346.33

COC(=O)C1=C(C)NC(C)=C(C1C1=C(C=CC=C1)[N+]([O-])=O)C(=O)OC

-20°C

Ice Packs

Small Compound