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Nigericin sodium salt - CAS 28643-80-3

Nigericin sodium salt - CAS 28643-80-3

SKU:MF-0043297-01

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  • Bioactivity

    Nigericin sodium salt is an antibiotic, an NLRP3 activator, and a cationic ion carrier. Nigericin sodium triggers the activation of the NALP3 inflammasome, which inhibits Golgi function and suppresses the growth of Gram-positive bacteria.

  • Target

    NOD, NOD-like Receptor (NLR), Pyroptosis, Potassium Channel, Antibiotic, Wnt/beta-catenin, Antibacterial

  • Related Pathways

    Membrane transporter/Ion channel, NF-κB, Immunology/Inflammation, Apoptosis, Stem Cells, Cytoskeletal Signaling, Microbiology/Virology

  • CAS Number

    28560

  • Purity

    0.9952

  • Molecular Formula

    C40H67NaO11

  • Molecular Weight

    746.94

  • SMILES

    [Na+].[H][C@@]1(C[C@H](C)[C@@]([H])(O1)[C@]1(C)CC[C@@]([H])(O1)[C@]1(C)C[C@@H](C)[C@]2(O1)O[C@]([H])(C[C@@]1([H])CC[C@H](C)[C@@]([H])(O1)[C@@H](C)C([O-])=O)C[C@@H](OC)[C@H]2C)[C@@]1([H])O[C@@](O)(CO)[C@H](C)C[C@@H]1C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Natural Product