Nilotinib hydrochloride - CAS 923288-95-3

Nilotinib hydrochloride (AMN-107 HCl) is an orally available Bcr-Abl tyrosine kinase inhibitor with antitumor activity for modulation of neuroinflammation and cognitive deficits, and may be used in studies of chronic myelogenous leukemia.

Autophagy, Bcr-Abl

Cytoskeletal Signaling, Autophagy, Tyrosine Kinase/Adaptors, Angiogenesis

923190

>99.99%

C28H23ClF3N7O

565.98

Cl.O=C(NC=1C=C(C=C(C1)C(F)(F)F)N2C=NC(=C2)C)C3=CC=C(C(=C3)NC=4N=CC=C(N4)C5=CN=CC=C5)C

-20°C

Ice Packs

Small Compound