Nintedanib-d8 - CAS 1624587-87-6

Nintedanib-d8 is a deuterated compound of Nintedanib. Nintedanib has a CAS number of 656247-17-5. Nintedanib is an inhibitor of the receptor tyrosine kinases VEGFR/FGFR/PDGFR (IC50s: 13-34/37-610/59/65 nM for VEGFR1-3, FGFR1-4, and PDGFRα/β, respectively) .

VEGFR, FGFR, PDGFR

Tyrosine Kinase/Adaptors, Angiogenesis

1624587-87-6

C31H25D8N5O4

547.67

N1C2=C(C=CC(C(OC)=O)=C2)/C(=C(/NC2=CC=C(N(C)C(=O)CN3C([2H])([2H])C([2H])([2H])N(C)C([2H])([2H])C3([2H])[2H])C=C2)\C2=CC=CC=C2)/C1=O

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