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Molfinity

Nirogacestat dihydrobromide - CAS 1962925-29-6

Nirogacestat dihydrobromide - CAS 1962925-29-6

MF-0036715-01

$741.47 USD
$512.20 USD $741.47 USD
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Product Details

  • Bioactivity

    Potent γ-secretase inhibitor (IC50 values are 1.2 and 6.2 nM in whole cell and cell-free assays, respectively) . Reduces Aβ in brain, CSF and plasma in mice and guinea pigs.

  • Target

    Apoptosis, Gamma-secretase, Others

  • Related Pathways

    Apoptosis, Proteases/Proteasome, Others, Neuroscience, Stem Cells

  • CAS Number

    1962925-29-6

  • Molecular Formula

    C27H43Br2F2N5O

  • Molecular Weight

    651.48

  • SMILES

    Br.Br.CCC[C@H](N[C@H]1CCc2cc(F)cc(F)c2C1)C(=O)Nc1cn(cn1)C(C)(C)CNCC(C)(C)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound