Nitracrine dihydrochloride hydrate - CAS 55429-45-3

Nitracrine (dihydrochloride hydrate), a 1-nitroacridine derivative, inhibits RNA synthesis, reversibly binds to DNA, and forms covalent adducts with DNA in vivo. It is a potent hypoxia-selective and antitumor agent in vitro, exhibiting cytotoxicity towards most cells [1] [2] [3].

DNA/RNA Synthesis

DNA Damage/DNA Repair, Cell Cycle/Checkpoint

55429-45-3

C18H24Cl2N4O3

415.31

CN(C)CCCNC1=C(C=CC=C2)C2=NC3=C1C([N+]([O-])=O)=CC=C3.Cl.O.Cl

-20°C

Ice Packs

Small Compound