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NLRP3-IN-10 - CAS 2641826-39-1

NLRP3-IN-10 - CAS 2641826-39-1

SKU:MF-0016307-01

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  • Bioactivity

    NLRP3-IN-10 (ZVN26391) is a potent NLRP3 inhibitor. NLRP3-IN-10 inhibits IL-1β release with an IC50 value of 251.1 nM. NLRP3-IN-10 attenuates ASC speck formation, leading to suppress activation of NLRP3 inflammasome.

  • Target

    NOD-like Receptor (NLR), NOD

  • Related Pathways

    NF-κB, Immunology/Inflammation

  • CAS Number

    2641786

  • Purity

    0.9963

  • Molecular Formula

    C17H14BrFO3

  • Molecular Weight

    365.19

  • SMILES

    COc1cc(\C=C\C(=O)c2ccc(F)cc2)c(OC)cc1Br

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound