Molfinity

NLRP3-IN-14 - CAS 2767369-80-0

SKU:MF-0146479-01

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Product Details

Bioactivity
NLRP3-IN-14 is a potent, selective inhibitor of the NLRP3 inflammasome, displaying a dissociation constant (K D) of 5.87 μM and an IC50 of 0.131 μM for inhibiting IL-1β release. It is applicable for inflammation research.
Target
Others, NOD-like Receptor (NLR)
Related Pathways
Others, Immunology/Inflammation
CAS Number
2767289
Molecular Formula
C27H28N2O4
Molecular Weight
444.52
SMILES
O=C1C(=O)C2=C(OC3=C2CCN(C3)CCCN4CCOCC4)C=5C=CC6=C(C=CC=C6C)C15
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound