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NLRP3-IN-17 - CAS 2254432-75-0

NLRP3-IN-17 - CAS 2254432-75-0

SKU:MF-0156598

Regular price $138.75 USD
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  • Bioactivity

    NLRP3-IN-17 is a potent, selective, and orally active inhibitor of the NLRP3 inflammasome with an IC50 of 7 nM, effectively inhibiting NLRP3-dependent IL-1β secretion in mice, making it valuable for chronic inflammatory disease research [1].

  • Target

    NOD-like Receptor (NLR)

  • Related Pathways

    Immunology/Inflammation

  • CAS Number

    2254357

  • Molecular Formula

    C21H22N4O2S

  • Molecular Weight

    394.49

  • SMILES

    N#CN=S(=O)(NC(=O)NC=1C2=C(C=C3C1CCC3)CCC2)C4=CC=C(C=C4)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound