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NLRP3-IN-19 - CAS 2238819-65-1
NLRP3-IN-19 - CAS 2238819-65-1
SKU:MF-0147173-01
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$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
JT001 (NLRP3-IN-19) is a potent, specific, and orally active NLRP3 inhibitor that impedes the assembly of the NLRP3 inflammasome, suppressing cytokine release and preventing pyroptosis. JT001 is utilized in research on nonalcoholic steatohepatitis and liver fibrosis [1].
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Target
NOD-like Receptor (NLR)
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Related Pathways
Immunology/Inflammation
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CAS Number
2238753
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Molecular Formula
C19H22N4O4S
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Molecular Weight
402.47
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SMILES
N(C(NS(=O)(=O)C1=C2N(N=C1)CCCO2)=O)C3=C4C(=CC5=C3CCC5)CCC4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound