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Molfinity

NLRP3-IN-28 - CAS 2922814-80-8

NLRP3-IN-28 - CAS 2922814-80-8

MF-0121045-01

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Product Details

  • Bioactivity

    NLRP3-IN-28 (compound N77) serves as a potent inhibitor of NLRP3, effectively blocking Nigericin-induced pyroptosis with an EC50 of 0.07μM. Additionally, it mitigates inflammatory reactions in vivo [1].

  • Target

    NOD-like Receptor (NLR), Pyroptosis

  • Related Pathways

    Apoptosis, Immunology/Inflammation

  • CAS Number

    2922814-80-8

  • Molecular Formula

    C12H9F3N2O3S

  • Molecular Weight

    318.27

  • SMILES

    OC1=C(C2=CC=C(S(C)(=O)=O)N=N2)C=CC(C(F)(F)F)=C1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound