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NLRP3-IN-38 - CAS 3033054-46-2

NLRP3-IN-38 - CAS 3033054-46-2

MF-0121049-01

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Product Details

  • Bioactivity

    NLRP3-IN-38 (Compound 18) serves as an inhibitor of the NOD-like receptor protein 3 (NLRP3), effectively blocking the activation of the NLRP3 inflammasome with an EC50 value of 23 nM [1].

  • Target

    NOD-like Receptor (NLR)

  • Related Pathways

    Immunology/Inflammation

  • CAS Number

    3033054-46-2

  • Molecular Formula

    C21H21F3N4O2

  • Molecular Weight

    418.41

  • SMILES

    OC1=C(C=2C3=C(C(=NN2)N4C[C@H](C)[C@@H](O)[C@H](C)C4)C=NC=C3)C=CC(C(F)(F)F)=C1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound