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NLRP3-IN-44 - CAS 3040298-34-5
NLRP3-IN-44 - CAS 3040298-34-5
SKU:MF-0122637-01
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Product Details
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Bioactivity
NLRP3-IN-44 (compound P33), an orally active (approximately 62%) and potent inhibitor of NLRP3, exhibits a dissociation constant (K D) of 17.5 nM. This compound is crucial in the research of diseases mediated by the NLRP3 inflammasome.
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Target
NOD-like Receptor (NLR)
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Related Pathways
Immunology/Inflammation
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CAS Number
3040298-34-5
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Molecular Formula
C25H30N4O3
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Molecular Weight
434.53
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SMILES
N(C1=C2C(=C(N=N1)C=3C(O)=C4C(=CC3)OC=C4)C5CCC2CC5)[C@H]6CN(CCO)CCC6
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound