NLRP3-IN-56 - CAS 3048421-42-4

NLRP3-IN-56 (compound 062) is an inhibitor of NLRP3. It effectively suppresses the secretion of IL-1β in THP-1 cells, demonstrating an IC50 of 9.7 nM. NLRP3-IN-56 is useful for research into NLRP3-mediated symptoms and/or diseases.

NOD-like Receptor (NLR)

Immunology/Inflammation

3048375

C20H18ClN3O3

383.83

N(C[C@@H](CO)O)C=1C2=C(C(=NN1)C3=C(O)C=C(Cl)C=C3)C=CC(C#CC)=C2

-20°C

Ice Packs

Small Compound