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NLRP3-IN-58 - CAS 2956014-05-2
NLRP3-IN-58 - CAS 2956014-05-2
SKU:MF-0142718-01
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$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
NLRP3-IN-58 (Compound DS15) acts as an inhibitor of NLRP3 inflammasome activation, with an IC50 value of 3.85 μM, and is capable of inhibiting 33% of IL-1β release at a concentration of 10 μM.
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Target
NOD-like Receptor (NLR), Interleukin
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Related Pathways
Immunology/Inflammation
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CAS Number
2956014-05-2
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Molecular Formula
C22H18ClN3O3S
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Molecular Weight
439.92
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SMILES
O=C(NC1=CC=CC(=C1)S(=O)(=O)NC=2C=CC=CC2)CC3=CNC=4C=C(Cl)C=CC43
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound