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NLRP3-IN-58 - CAS 2956014-05-2

NLRP3-IN-58 - CAS 2956014-05-2

SKU:MF-0142718-01

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  • Bioactivity

    NLRP3-IN-58 (Compound DS15) acts as an inhibitor of NLRP3 inflammasome activation, with an IC50 value of 3.85 μM, and is capable of inhibiting 33% of IL-1β release at a concentration of 10 μM.

  • Target

    NOD-like Receptor (NLR), Interleukin

  • Related Pathways

    Immunology/Inflammation

  • CAS Number

    2956014-05-2

  • Molecular Formula

    C22H18ClN3O3S

  • Molecular Weight

    439.92

  • SMILES

    O=C(NC1=CC=CC(=C1)S(=O)(=O)NC=2C=CC=CC2)CC3=CNC=4C=C(Cl)C=CC43

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound