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Molfinity

NLRP3-IN-61 - CAS 3060585-94-3

NLRP3-IN-61 - CAS 3060585-94-3

MF-0112148-01

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Product Details

  • Bioactivity

    NLRP3-IN-61 (Compound 1) is an inhibitor of NLRP3. It suppresses pyroptosis in THP-1 cells with an IC50 of 12.6 nM and inhibits IL-β release with an IC50 of 25.3 nM.

  • Target

    NOD-like Receptor (NLR), Pyroptosis

  • Related Pathways

    Immunology/Inflammation, Apoptosis

  • CAS Number

    3060488

  • Molecular Formula

    C21H21N3O3

  • Molecular Weight

    363.41

  • SMILES

    OC=1C(C=2N=C3C(OC(=N3)[C@@H]4CCC(=O)NC4)=CC2)=C(C)C=C5C1CCC5

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound